What explains human consequences of weather-related disaster? Here, we explore how core socioeconomic, political, and security conditions shape flood-induced displacement worldwide since 2000. In-sample regression analysis shows that extreme displacement levels are more likely in contexts marked by low national income levels, nondemocratic political systems, high local economic activity, and prevalence of armed conflict. The analysis also reveals large residual differences across continents, where flood-induced displacement in the Global South often is much more widespread than direct human exposure measures would suggest. However, these factors have limited influence on our ability to accurately predict flood displacement on new data, pointing to important, hard-to-operationalize heterogeneity in flood impacts across contexts and critical data limitations. Although results are consistent with an interpretation that the sustaina￾ble development agenda is beneficial for disaster risk reduction, better data on soci￾etal consequences of natural hazards are critically needed to support evidence-based decision-making.